Quick post today because I’m off to the hospital soon. I wanted to share this article I was reading because it has shed some light on the old theory that calorie restriction is beneficial to health as well as new claims that ketosis helps reduce inflammation.
There are so many diet and health claims and so few studies to support any of the data. Currently, the Mediterranean diet has the best success rate in reducing heart disease and improving overall health. But there are still hundreds of other diets that tout longevity and improved health: the DASH diet, low-carb diets, intermittent fasting, and so-on.
My take on all of this is to go back to what one of my favorite people, Micheal Pollan has said:
Anyway, one of the only “diet strategies” (if you can call it that) that has legit data behind it’s success in improving overall health is caloric restriction. Calorie restriction is associated with longer lifespan and has been shown many times to increase longevity in mice. But who wants to eat less? Not me! 🙂
I never really understood why calorie restriction would be beneficial to the body, but this article sheds some light on that. It also supports one of the new ‘trendy’ diets, the ketogenic diet.
According to this study, The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease, published in Nature Medicine, the metabolic byproducts of fasting reduce inflammatory mediators in the body.
When your body doesn’t have glucose available (in fasting and carbohydrate depleted states) you make ketones to provide fuel for the brain and the rest of your body. In this study, the ketone beta-hydroxybutyrate (BHB) was studied as it relates to inflammatory markers. The authors showed that BHB actually inhibits an inflammatory complex that has been implicated as the driver behind many chronic illnesses including diabetes and Alzheimers.
I don’t know if this small study has convinced me to start intermittent fasting or caloric restriction (there is no way I could make it through the day if I was hungry!!) but it is interesting to see what might be happening on a cellular level. And, it does give more credit to the ketogenic diet fans out there 🙂
What do you think about all the ketosis hype?